ʻO Pharmacodynamics enrofloxacin kahi lāʻau bactericidal ākea ākea no nā holoholona fluoroquinolone. He hopena maikaʻi loa ia ma ka escherichia coli, salmonella, klebsiella, brucella, pasteurella, actinobacillus pleuropneumoniae, erysipelas, proteus, serratia marcescens, corynebacterium pyogenes, portococcus septicus, staphylococcus aureus, mycoplasma, a me nā mea nāwaliwali loa. aeruginosa a me streptococcus, a me ka hopena nāwaliwali i ka bacteria anaerobic. Loaʻa iā ia ka hopena post-antibacterial ma luna o nā maʻi bacteria koʻikoʻi. ʻO ka hana antibacterial o kēia huahana ke kāohi i ka enzyme rotation DNA bacteria, hoʻopilikia i ka replication DNA bacteria, transcription a me ka hoʻoponopono hou ʻana, ʻaʻole hiki i ka bacteria ke ulu a hoʻohua maʻamau a make.
ʻO Pharmacokinetics ka intramuscular absorption o kēia huahana he wikiwiki a piha, me ka bioavailability o 91.9% i nā puaʻa a me 82% i nā bipi waiu. Hoʻolaha nui ʻia i nā holoholona a hiki ke komo maikaʻi i nā ʻiʻo a me nā wai o ke kino, koe wale ka wai cerebrospinal, ʻoi aku ka kiʻekiʻe o ka nui o nā lāʻau i loko o nā ʻiʻo āpau ma mua o ka plasma. ʻO ka metabolism o ka ate ka mea nui e hana i ka ciprofloxacin ma ka wehe ʻana i ka ethyl o ke apo 7-piperazine, a ukali ʻia e ka oxidation a me ka glucuronic acid binding. Hoʻokuʻu ʻia ia e nā puʻupaʻa (e ka renal tubule secretion a me ka kānana glomerular), a ʻo 15% a 50% e hoʻokuʻu ʻia mai ka mimi i kona ʻano kumu. ʻOkoʻa ka hapalua o ke ola ma nā ʻano ʻano like ʻole a me nā ala like ʻole o ka hoʻokele. ʻO ka hoʻopau ʻana i ka hapalua o ke ola ma hope o ka hoʻokele intramuscular he 5.9 mau hola i nā bipi, 9.9 mau hola i nā lio, 1.5 a 4.5 mau hola i nā hipa, a me 4.6 mau hola i ka puaʻa.
1. He hopena synergistic kēia huahana ke hoʻohana ʻia me aminoglycoside a i ʻole penicillin ākea ākea.
2. ʻO nā ion metala kaumaha e like me ca2+, mg2+, fe3+ a me al3+ canchelate me kēia huahana a pili i ka absorption.
3. Ke hui pū ʻia me ka theophylline a me ka caffeine, hiki iā ia ke hōʻemi i ka helu paʻa o ka protein plasma, hoʻonui maʻamau i ka neʻe ʻana o ka theophylline a me ka caffeine i loko o ke koko, a hiki ke ʻike ʻia nā hōʻailona make theophylline.
4. ʻO kēia huahana ka hopena o ke kāohi ʻana i nā enzymes lāʻau lapaʻau, hiki ke hōʻemi i ka helu hoʻomaʻemaʻe o nā lāʻau lapaʻau i hoʻopili nui ʻia i loko o ke ake a hoʻonui i ka hoʻonui ʻana i ke koko.
ʻO nā lāʻau antibacterial Fluoroquinolone. Hoʻohana ʻia no nā maʻi maʻi bacteria a me nā moa a me ka maʻi mycoplasma.
Intramuscular injection: Hoʻokahi pānaʻi, 0.025ml no 1kg ke kaumaha o ke kino o nā pipi, hipa a me nā puaʻa; 0.025 ~ 0.05ml no nā ʻīlio, nā pōpoki a me nā lākeke. E hoʻohana i 1 a 2 mau manawa i ka lā no 2 a 3 mau lā.
1. ʻO ka hoʻohaʻahaʻa ʻana o ka cartilage i nā holoholona ʻōpio, e pili ana i ka ulu ʻana o ka iwi a me ka ʻopa a me ka ʻeha.
2. ʻO ka hopena o ka ʻōnaehana digestive e pili ana i ka luaʻi ʻana, ka pau ʻana o ka ʻai, ka maʻi maʻi a me ka wikiwiki.
3. ʻO nā hopena o ka ʻili he erythema, pruritus, urticaria a me photosensitivity.
4. ʻIke ʻia nā hopena maʻi, ataxia, hopu i nā ʻīlio a me nā pōpoki.
1. Loaʻa iā ia ka hopena excitatory ma luna o ka ʻōnaehana kikowaena, e hoʻoulu ai i ka epileptic seizures, a pono e hoʻohana me ka akahele i nā ʻīlio epileptic.
2. Pono e hoʻohana me ka akahele i nā mea ʻai a me nā holoholona me ka hana ʻino ʻole, hiki ke hana i ka mimi crystalline i kekahi manawa.
3. ʻAʻole kūpono kēia huahana no nā lio. He mau mea hoʻonāukiuki i loko o ke kino.
4. ʻAʻole pono e hoʻohana ʻia kēia huahana i nā ʻīlio ma mua o 8 mau pule.
5. Ke piʻi aʻe nei nā ʻano lāʻau kūʻē o kēia huahana a ʻaʻole pono e hoʻohana ʻia i nā ʻano subtherapeutic no ka manawa lōʻihi.
