No nā lāʻau lapaʻau pharmacodynamic lincomycin, he lāʻau bacteriostatic, ʻo nā maʻi maʻi maʻamau e komo pū me staphylococcus aureus (me nā penicillin-resistant strains), streptococcus, pneumococcus, bacillus anthracis, erysipelas suis, kekahi mycoplasma (mycoplasma suis mycoplasma, mycoplasma suis pneumonia suis, mycoplasma suis pneumonia suis, mycoplasma suis pneumoniae, mycoplasma suis pneumoniae, mycoplasma suis pneumoniae, mycoplasma suis pneumoniae, mycoplasma suis pneumoniae). leptospirosis a me ka bacteria anaerobic (e like me clostridium difficile, clostridium tetanus, clostridium percapsulatus a me ka hapa nui o actinomyces). Hana nui ia ma ka 50s subunit o ka ribosome bacteria, a hoʻohana i kahi hopena antibacterial ma ke kāohi ʻana i ka hoʻonui ʻana o ke kaulahao peptide a pili i ka synthesis protein.
Ua wikiwiki ka absorption ma hope o ka intramuscular injection, me ka hoʻokahi intramuscular injection o 11mg / kg i loko o nā puaʻa a me kahi kiʻekiʻe o ke koko o 6.25μg / ml. ʻO ka nui o ka hoʻopaʻa ʻana i ka protein plasma he 57%-72%. Hoʻolaha nui ʻia i loko o vivo, me ka nui o ka hāʻawi ʻana o 2.8 l / kg i nā puaʻa. Hoʻolaha nui ʻia ia i loko o nā wai kino a me nā ʻiʻo (me ka iwi), ʻo ia ka mea kiʻekiʻe loa o ke akepaʻa a me nā puʻupaʻa, a ʻoi aku ka kiʻekiʻe o ka nui o ka lāʻau lapaʻau ma mua o ka serum i ka manawa like. Hiki iā ia ke komo i loko o ka placenta, akā ʻaʻole maʻalahi ke komo ʻana i ka pale koko-lolo, a paʻakikī ke hiki i kahi ʻano kūpono o ka lāʻau i loko o ka wai cerebrospinal i ka wā e ulu ai ka mumū. Hiki ke hāʻawi ʻia i ka waiū, a ʻo ka ʻike i ka waiū e like me ka plasma. Hoʻopili ʻia kahi hapa o ka lāʻau lapaʻau i loko o ke akepaʻa, a hoʻokuʻu ʻia ke ʻano lāʻau lapaʻau a me kāna mau metabolites ma o ka bile, mimi a me ka waiū. Hiki ke hoʻopaneʻe ʻia ka hoʻokuʻu ʻana i loko o ka stool no kekahi mau lā, no laila he hopena pale i nā microorganism sensitive o ka ʻōpū.
1. Ke hui pū ʻia me ka gentamicin, loaʻa iā ia ka hopena synergistic i nā hua bacteria gram-positive e like me staphylococcus a me streptococcus.
2. Ke hui pū ʻia me nā aminoglycosides a me nā antibiotics polypeptide, hiki ke hoʻonui i ka hopena pale ma ka hui neuromuscular. Hoʻohui pū ʻia me ka erythromycin ka hopena antagonistic, no ka mea he like ke kahua o ka hana, a ʻoi aku ka ikaika o ka erythromycin i ka 50s subunit o nā ribosomes bacterial ma mua o kēia huahana.
3. ʻAʻole pono e hui pū ʻia me nā lāʻau antidiarrheal e kāohi ai i ka peristalsis ʻōpū a loaʻa i ka pālolo keʻokeʻo. 4. Loaʻa ka like ʻole me kanamycin, neomycin, etc.
ʻO nā lāʻau lapaʻau Lincoamine. No ka maʻi bacteria gram-positive, hiki ke hoʻohana ʻia no treponemosis a me mycoplasma a me nā maʻi ʻē aʻe.
Intramuscular injection: One dose, 0.0165 ~ 0.033ml no 1kg kino kaumaha no nā lio a me nā bipi, 0.033ml no nā hipa a me nā puaʻa, hoʻokahi manawa i ka lā; 0.033ml no nā ʻīlio a me nā pōpoki, ʻelua i ka lā, no 3 a 5 mau lā.
Hiki ke hoʻoulu ʻia ka maʻi maʻi maʻi a i ʻole nā stools palupalu. ʻOiai kakaʻikahi, pono e lawe ʻia nā mea e pono ai e pale i ka dehydration inā hiki mai.
